Source Themes

Debar A sequence‐by‐sequence denoiser for COI‐5P DNA barcode data

DNA barcoding and metabarcoding are now widely used to advance species discovery and biodiversity assessments. High-throughput...

Genomic basis of deep‐water adaptation in Arctic Charr (Salvelinus alpinus) morphs

The post-glacial colonization of Gander Lake in Newfoundland, Canada, by Arctic Charr (Salvelinus alpinus) provides the opportunity to study the genomic basis of adaptation...

Genomic evidence of past and future climate-linked loss in a migratory Arctic fish

Despite widespread biodiversity losses, an understanding of how most taxa will respond to future climate change is lacking. Here we integrate...

Alignment-free classification of COI DNA barcode data with the Python package Alfie

Characterization of biodiversity from environmental DNA samples and bulk metabarcoding data is hampered by off-target sequences that can...

Limited genetic parallelism underlies recent, repeated incipient speciation in geographically proximate populations of an Arctic fish (Salvelinus alpinus)

The genetic underpinnings of incipient speciation, including the genomic mechanisms which contribute to morphological and ecological differentiation and reproductive isolation, remain...

coil an R package for cytochrome C oxidase I (COI) DNA barcode data cleaning, translation, and error evaluation

Biological conclusions based on DNA barcoding and metabarcoding analyses can be strongly influenced by the methods utilized for data generation and curation, leading to varying levels of...

Resolving fine-scale population structure and fishery exploitation using sequenced microsatellites in a northern fish

The resiliency of populations and species to environmental change is dependent on the maintenance of genetic diversity, and as such, quantifying diversity is...

Association of Biologic Prescribing for Inflammatory Bowel Disease With Industry Payments to Physicians

Biologic medications account for the majority of outpatient treatment expenditures for inflammatory bowel disease. The US Food and Drug Administration (FDA) approved adalimumab...

Design and characterization of an 87k SNP genotyping array for Arctic charr (Salvelinus alpinus)

We have generated a high-density, high-throughput genotyping array for characterizing genome-wide variation in Arctic charr (Salvelinus alpinus). Novel single nucleotide polymorphisms...

A SNP Based Linkage Map of the Arctic Charr (Salvelinus alpinus) Genome Provides Insights into the Diploidization Process After Whole Genome Duplication

Diploidization, which follows whole genome duplication events, does not occur evenly across the genome. In salmonid fishes certain pairs of homeologous chromosomes preserve...